Tet 42, a novel tetracycline resistance determinant isolated from deep terrestrial subsurface bacteria.

نویسندگان

  • Mindy G Brown
  • Elizabeth H Mitchell
  • David L Balkwill
چکیده

Tet 42, a novel tetracycline resistance determinant from deep subsurface bacteria, was characterized and found to have a 30% sequence similarity to TetA(Z). The protein is a putative efflux pump that shares characteristics with previously characterized pumps, including a divergently transcribed TetR repressor, a conserved GxxSDRxGRR motif, and transmembrane domains.

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عنوان ژورنال:
  • Antimicrobial agents and chemotherapy

دوره 52 12  شماره 

صفحات  -

تاریخ انتشار 2008